Smoking preceded pulmonary involvement in adults with Langerhans cell histiocytosis diagnosed in childhood

Acta Paediatr. 2000 Nov;89(11):1389-92. doi: 10.1080/080352500300002642.

Abstract

Two patients with childhood Langerhans cell histiocytosis (LCH) (aged 2 and 6 y at diagnosis) in whom pulmonary involvement was diagnosed in adulthood, 23 and 12 y later, respectively, are presented. In each patient, smoking preceded the diagnosis of pulmonary involvement by 3 y, providing further evidence that smoking is a risk factor in the development of pulmonary LCH.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Child
  • Child, Preschool
  • Female
  • Histiocytosis, Langerhans-Cell* / diagnosis
  • Histiocytosis, Langerhans-Cell* / pathology
  • Histiocytosis, Langerhans-Cell* / therapy
  • Humans
  • Lung / pathology
  • Male
  • Radiography, Thoracic
  • Risk Factors
  • Smoking / adverse effects*
  • Time Factors
  • Tomography, X-Ray Computed