To examine the relation between social support and appraisal of life events in predicting adaptive, externalizing, and internalizing behavior in 265 school-age children, child-report on both a global and a significant other measure of social support was used. Life event scores were separated into events endorsed as negative and events endorsed as positive by the child. Using hierarchical regression analyses, the present study tested two models: main effects and moderator models of the relation between life events, social support, and behavioral outcome. Support was found for global social support and positive life events in predicting adaptive, externalizing, and internalizing behavior. Gender differences were also found. Support was found for both the main effects and moderator models of the association between life events and global social support. Appraisal of life events as positive appears to compensate for lower levels of global social support. Appraisal is discussed as a possible protective factor from maladjustment after exposure to major life events.