Abstract
We report a 13-year-old girl with leukaemia and Wernicke's encephalopathy induced by total parenteral nutrition. MRI showed unusual bilateral lesions of the caudate nuclei and cerebral cortex, as well as typical lesions surrounding the third ventricle and aqueduct. After intravenous thiamine, the patient improved, and the abnormalities on MRI disappeared.
MeSH terms
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Acute Disease
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Adolescent
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Caudate Nucleus / pathology*
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Cerebral Cortex / pathology*
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Female
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Humans
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Leukemia, Myeloid / complications
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Leukemia, Myeloid / therapy*
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Magnetic Resonance Imaging*
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Parenteral Nutrition, Total / adverse effects*
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Thiamine / therapeutic use
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Wernicke Encephalopathy / drug therapy
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Wernicke Encephalopathy / etiology*
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Wernicke Encephalopathy / pathology