Niemann-Pick type C: a disorder of cellular cholesterol trafficking

Biochim Biophys Acta. 2000 Dec 15;1529(1-3):331-9. doi: 10.1016/s1388-1981(00)00158-x.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Brain / metabolism
  • Brain / pathology
  • Carrier Proteins*
  • Cell Line
  • Cell Membrane / metabolism
  • Cholesterol / metabolism*
  • Disease Models, Animal
  • Endoplasmic Reticulum / metabolism
  • Gene Expression Regulation
  • Genetic Therapy
  • Humans
  • Intracellular Signaling Peptides and Proteins
  • Liver / metabolism
  • Lysosomes / metabolism
  • Membrane Glycoproteins*
  • Mice
  • Mice, Inbred BALB C
  • Models, Molecular
  • Mutation
  • Niemann-Pick Diseases / epidemiology
  • Niemann-Pick Diseases / genetics*
  • Niemann-Pick Diseases / metabolism
  • Proteins / chemistry
  • Proteins / genetics*
  • Spleen / metabolism
  • United States / epidemiology

Substances

  • Carrier Proteins
  • Intracellular Signaling Peptides and Proteins
  • Membrane Glycoproteins
  • NPC1 protein, human
  • Npc1 protein, mouse
  • Proteins
  • Cholesterol