Otogenic brain abscess: review of 41 cases

Otolaryngol Head Neck Surg. 2000 Dec;123(6):751-5. doi: 10.1067/mhn.2000.107887.

Abstract

Forty-one patients in whom otogenic brain abscess was diagnosed and has been treated since 1968 are presented. Sixty-five percent of the patients were between 5 and 15 years of age. All patients had chronic otitis media, and 95% had cholesteatoma. Abscess was located in the temporal lobe in 54%, in the cerebellum in 44%, and in both locations in 2% of the cases. Most patients had radical mastoidectomy and evacuation of the abscess through the mastoidectomy (61%). In addition to mastoidectomy, burr hole drainage was used in 20% and craniotomy in 15%. The most common micro-organism involved was Proteus. Overall mortality in this series is 29%, but after 1976, when CT became available for the diagnosis and follow-up, the mortality rate was reduced to 10%.

MeSH terms

  • Adolescent
  • Adult
  • Anti-Bacterial Agents
  • Brain Abscess / microbiology*
  • Brain Abscess / mortality
  • Brain Abscess / therapy
  • Cerebellar Diseases / microbiology*
  • Cerebellar Diseases / mortality
  • Cerebellar Diseases / therapy
  • Child
  • Child, Preschool
  • Cholesteatoma, Middle Ear / complications*
  • Cholesteatoma, Middle Ear / therapy
  • Chronic Disease
  • Combined Modality Therapy
  • Craniotomy
  • Drainage
  • Drug Therapy, Combination / therapeutic use
  • Female
  • Humans
  • Male
  • Mastoid / surgery
  • Middle Aged
  • Otitis Media / complications*
  • Otitis Media / therapy
  • Proteus Infections / complications*
  • Proteus Infections / therapy
  • Retrospective Studies
  • Staphylococcal Infections / complications*
  • Staphylococcal Infections / therapy
  • Streptococcal Infections / complications*
  • Streptococcal Infections / therapy
  • Survival Analysis
  • Temporal Lobe*
  • Tomography, X-Ray Computed
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents