Signal recognition and transduction mediated by the tomato Pto kinase: a paradigm of innate immunity in plants

Microbes Infect. 2000 Nov;2(13):1591-7. doi: 10.1016/s1286-4579(00)01315-0.

Abstract

Plant disease resistance is the result of an innate host defense mechanism, which relies on the ability of the plant to recognize pathogen invasion and to efficiently mount defense responses. In tomato, resistance to the pathogen Pseudomonas syringae is mediated by the specific interaction between the plant serine/threonine kinase Pto and the bacterial protein AvrPto. This article reviews molecular and biochemical properties that confer to Pto the capability to function as an intracellular receptor and to activate a signaling cascade leading to the induction of defense responses.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Bacterial Proteins / metabolism
  • Lycopersicon esculentum / enzymology
  • Lycopersicon esculentum / immunology
  • Plant Diseases / microbiology
  • Plant Proteins*
  • Plants / immunology*
  • Plants / microbiology
  • Protein-Serine-Threonine Kinases / metabolism
  • Pseudomonas / chemistry
  • Pseudomonas / metabolism
  • Signal Transduction

Substances

  • Bacterial Proteins
  • Plant Proteins
  • avrPto protein, Pseudomonas syringae
  • Pto protein, Lycopersicon
  • Protein-Serine-Threonine Kinases