Abstract
The clinical and laboratory features of the seven known patients with heavy chain disease showed that all but one had chronic lymphocytic leukemia. Two common and striking features are the presence of kappa-type Bence Jones proteins and vacuolated plasma cells in the marrow.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Adult
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Aged
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Bence Jones Protein / analysis
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Bone Marrow Examination
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Female
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Heavy Chain Disease / complications
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Heavy Chain Disease / diagnosis*
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Heavy Chain Disease / immunology
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Humans
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Immunoglobulin Fragments*
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Immunoglobulin M / analysis*
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Leukemia, Lymphoid / complications
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Leukemia, Lymphoid / immunology
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Male
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Middle Aged
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Plasma Cells
Substances
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Immunoglobulin Fragments
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Immunoglobulin M
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Bence Jones Protein