Influence of dietary ginger (Zingiber officinales Rosc) on antioxidant defense system in rat: comparison with ascorbic acid

Indian J Exp Biol. 2000 Jun;38(6):604-6.

Abstract

Ginger (Z. officinale; 1% w/w) significantly lowered lipid peroxidation by maintaining the activities of the antioxidant enzymes--superoxide dismutase, catalase and glutathione peroxidase in rats. The blood glutathione content was significantly increased in ginger fed rats. Similar effects were also observed after natural antioxidant ascorbic acid (100 mg/kg, body wt) treatment. The results indicate that ginger is comparatively as effective as ascorbic acid as an antioxidant.

Publication types

  • Comparative Study
  • Evaluation Study

MeSH terms

  • Administration, Oral
  • Animal Feed
  • Animals
  • Antioxidants / pharmacology*
  • Ascorbic Acid / pharmacology*
  • Catalase / blood
  • Ginger / chemistry*
  • Glutathione / blood
  • Glutathione Peroxidase / blood
  • Glutathione Transferase / blood
  • Lipid Peroxidation / drug effects*
  • Male
  • Plants, Medicinal*
  • Powders
  • Rats
  • Rats, Wistar
  • Superoxide Dismutase / blood
  • Thiobarbituric Acid Reactive Substances / analysis

Substances

  • Antioxidants
  • Powders
  • Thiobarbituric Acid Reactive Substances
  • Catalase
  • Glutathione Peroxidase
  • Superoxide Dismutase
  • Glutathione Transferase
  • Glutathione
  • Ascorbic Acid