Anti-E in pregnancy

BJOG. 2000 Nov;107(11):1436-8. doi: 10.1111/j.1471-0528.2000.tb11662.x.


Since the introduction of anti-Rhesus (Rh) D prophylaxis for RhD-negative women, other Rh and non-Rh red cell alloantibodies have become relatively more important and are now responsible for the greater proportion of haemolytic disease of the newborn. Anti-C and anti-E are the most commonly implicated non-D Rh antibodies in the pathogenesis of haemolytic disease of the newborn'. In 1977 Pepperell et al. reported the outcome of 44 women with anti-E. This is the only published series that investigates the implications of anti-E during pregnancy. The present report presents a retrospective study of the outcome of 122 pregnancies in which anti-E was the sole alloantibody detected.

MeSH terms

  • Erythroblastosis, Fetal / diagnosis*
  • Female
  • Fetal Blood / chemistry*
  • Hemoglobins / metabolism*
  • Humans
  • Isoantibodies / blood*
  • Pregnancy
  • Pregnancy Complications, Hematologic / diagnosis*
  • Pregnancy Outcome
  • Retrospective Studies


  • Hemoglobins
  • Isoantibodies