Biosynthesis of the dimethylallyl moiety of glabrol in Glycyrrhiza glabra hairy root cultures via a non-mevalonate pathway

Y Asada; W Li; T Yoshikawa

doi:10.1016/s0031-9422(00)00327-7

Biosynthesis of the dimethylallyl moiety of glabrol in Glycyrrhiza glabra hairy root cultures via a non-mevalonate pathway

Phytochemistry. 2000 Oct;55(4):323-6. doi: 10.1016/s0031-9422(00)00327-7.

Authors

Y Asada¹, W Li, T Yoshikawa

Affiliation

¹ School of Pharmaceutical Sciences, Kitasato University, Tokyo, Japan. asaday@pharm.kitasato-u.ac.jp

PMID: 11117880
DOI: 10.1016/s0031-9422(00)00327-7

Abstract

Incorporation of [1-13C]glucose indicates that the biosynthesis of the hemiterpene moiety of glabrol, the main prenylated flavanone in the hairy root cultures of Glycyrrhiza glabra, proceeds via a glyceraldehyde/pyruvate non-mevalonate pathway.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Flavonoids / biosynthesis*
Flavonoids / metabolism
Glyceraldehyde / metabolism
Glycyrrhiza / metabolism*
Magnetic Resonance Spectroscopy
Mevalonic Acid / metabolism
Plant Roots / metabolism
Plants, Medicinal*
Pyruvates / metabolism

Substances

Flavonoids
Pyruvates
Glyceraldehyde
glabrol
Mevalonic Acid