Effects of posture on sympathetic nervous modulation in patients with chronic heart failure

Lancet. 2000 Nov 25;356(9244):1822-3. doi: 10.1016/S0140-6736(00)03240-2.


We investigated which recumbent position is preferred by patients with chronic heart failure (CHF) and whether sympathetic nervous modulation differs in three recumbent positions. We assessed 12 patients with CHF by spectral analysis of heart-rate variability and measurement of plasma norepinephrine concentrations. The right lateral decubitus position was preferred for significantly longer periods than the left lateral decubitus and supine positions. Sympathetic nervous modulation was most attenuated in the right lateral decubitus position. The right lateral decubitus position preferred by patients with CHF may be a self-protective mechanism to control increased sympathetic nervous modulation.

Publication types

  • Clinical Trial
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Heart Failure / physiopathology*
  • Heart Rate
  • Humans
  • Male
  • Middle Aged
  • Norepinephrine / blood
  • Posture*
  • Sympathetic Nervous System*


  • Norepinephrine