Review
doi: 10.1016/s0966-842x(00)01833-3.
Two-component systems in Pseudomonas aeruginosa: why so many?
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- PMID: 11121759
- DOI: 10.1016/s0966-842x(00)01833-3
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Review
Two-component systems in Pseudomonas aeruginosa: why so many?
Trends Microbiol.
2000 Nov.
Abstract
Screening the Pseudomonas aeruginosa genome has led to the identification of the highest number of putative genes encoding two-component regulatory systems of all bacterial genomes sequenced to date (64 and 63 encoding response regulators and histidine kinases, respectively). Sixteen atypical kinases, among them 11 devoid of an Hpt domain, and three independent Hpt modules were retrieved. These data suggest that P. aeruginosa possesses complex control strategies with which to respond to environmental challenges.
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