Signal transduction during fertilization in the unicellular green alga, Chlamydomonas

Curr Opin Microbiol. 2000 Dec;3(6):596-602. doi: 10.1016/s1369-5274(00)00146-6.

Abstract

Sexual reproduction in the green alga, Chlamydomonas, is regulated by environmental conditions and by cell-cell interactions. After gametogenesis, flagellar adhesion between gametes triggers gamete activation, leading to cell fusion and zygote formation. Recent studies have identified new molecular events that underlie signal transduction during Chlamydomonas fertilization, including expression of a sex-determining protein, phosphorylation of a homeodomain protein, activity of a kinesin II and regulated translocation of an aurora/Ip11-like protein kinase from the cell body to the flagella.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Aurora Kinases
  • Calcium-Binding Proteins / metabolism
  • Chlamydomonas / growth & development
  • Chlamydomonas / physiology*
  • Flagella / metabolism
  • Gametogenesis
  • Germination
  • Homeodomain Proteins / metabolism
  • Kinesin
  • Muscle Proteins / metabolism
  • Plant Proteins / metabolism
  • Protein-Serine-Threonine Kinases / metabolism
  • Signal Transduction

Substances

  • Calcium-Binding Proteins
  • Homeodomain Proteins
  • Muscle Proteins
  • Plant Proteins
  • kinesin-II
  • Aurora Kinases
  • Protein-Serine-Threonine Kinases
  • Kinesin