Vegetative incompatibility in filamentous fungi: Podospora and Neurospora provide some clues

Curr Opin Microbiol. 2000 Dec;3(6):608-12. doi: 10.1016/s1369-5274(00)00148-x.


In filamentous fungi, vegetative cell fusion between genotypically distinct individuals leads to a cell-death reaction known as vegetative or heterokaryon incompatibility. Genes involved in this reaction have been characterised molecularly. We can now begin to get a better understanding of the mechanism and the biological significance of this intriguing phenomenon.

Publication types

  • Review

MeSH terms

  • Amino Acid Sequence
  • Ascomycota / genetics
  • Ascomycota / physiology*
  • Fungal Proteins / genetics
  • Genes, Fungal*
  • Prions / genetics
  • Sequence Alignment


  • Fungal Proteins
  • Prions