Long-term results of stapled and hand-sewn anastomoses in patients with Crohn's disease

Dig Surg. 2000;17(5):493-6. doi: 10.1159/000051946.


Aim: This study aimed at determining the reoperation rates of patients with anastomoses for Crohn's disease. The outcome of patients undergoing stapled anastomoses was compared with that of patients having hand-sewn anastomoses.

Methods: Sixty-three patients undergoing intestinal resection for Crohn's disease at our institution from 1987 to 1996 were studied in a prospective, randomized trial. The group undergoing stapling comprised 30 patients and 37 anastomoses. The group with a hand-sewn anastomosis comprised 33 patients and 45 anastomoses. The median follow-up period was 87 (range 36-140) months.

Results: There were no significant differences in operative indications or patients' age and sex between the groups. There was a significant difference in cumulative recurrences between the groups (Cox-Mantel test: p = 0.022).

Conclusion: A stapled anastomosis after resection for Crohn's disease may delay reoperation in patients with symptomatic recurrence.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Adolescent
  • Adult
  • Anastomosis, Surgical / methods
  • Crohn Disease / surgery*
  • Double-Blind Method
  • Female
  • Humans
  • Intestine, Small / surgery*
  • Male
  • Middle Aged
  • Prospective Studies
  • Reoperation
  • Surgical Stapling*
  • Treatment Outcome