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, 14 (24), 3075-86

Hormones in Male Sexual Development


Hormones in Male Sexual Development

S Nef et al. Genes Dev.


Classical embryology has provided a clear view of the timing and hormonal cues that govern sexual differentiation. Molecular biology has added important details to this picture. The cloning of SRY, MIS, and INSL3 provide insight into the molecular signals that provide important cues at the cellular level. Continued understanding of these pathways may provide the necessary information to one day reverse defects of sexual differentiation.

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