RISSC: a novel database for ribosomal 16S-23S RNA genes spacer regions

Nucleic Acids Res. 2001 Jan 1;29(1):178-80. doi: 10.1093/nar/29.1.178.


A novel database, under the acronym RISSC (Ribosomal Intergenic Spacer Sequence Collection), has been created. It compiles more than 1600 entries of edited DNA sequence data from the 16S-23S ribosomal spacers present in most prokaryotes and organelles (e.g. mitochondria and chloroplasts) and is accessible through the Internet (http://ulises.umh.es/RISSC), where systematic searches for specific words can be conducted, as well as BLAST-type sequence searches. Additionally, a characteristic feature of this region, the presence/absence and nature of tRNA genes within the spacer, is included in all the entries, even when not previously indicated in the original database. All these combined features could provide a useful documentation tool for studies on evolution, identification, typing and strain characterization, among others.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • DNA, Ribosomal Spacer / genetics*
  • Databases, Factual*
  • Internet
  • RNA, Ribosomal, 16S / genetics*
  • RNA, Ribosomal, 23S / genetics*
  • Sequence Alignment


  • DNA, Ribosomal Spacer
  • RNA, Ribosomal, 16S
  • RNA, Ribosomal, 23S