Recognition of another member of the malignant catarrhal fever virus group: an endemic gammaherpesvirus in domestic goats

J Gen Virol. 2001 Jan;82(Pt 1):227-232. doi: 10.1099/0022-1317-82-1-227.


A novel gammaherpesvirus in goats that is herein tentatively designated as caprine herpesvirus-2 was identified based on the sequence of a fragment from the herpesvirus DNA polymerase gene. Sequence alignment analysis revealed that the virus sequence isolated from goats was 67% identical to the homologous sequence from alcelaphine herpesvirus-1, 71% identical to ovine herpesvirus-2 and 73% identical to a recently recognized herpesvirus causing malignant catarrhal fever in white-tailed deer. Combined serological and PCR-survey data demonstrated that this virus is endemic in goats and its transmission pattern may be similar to that of ovine herpesvirus-2 in sheep.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Cloning, Molecular
  • Consensus Sequence
  • Disease Outbreaks / veterinary*
  • Gammaherpesvirinae / classification
  • Gammaherpesvirinae / genetics
  • Gammaherpesvirinae / isolation & purification*
  • Genome, Viral
  • Goat Diseases / epidemiology
  • Goat Diseases / virology*
  • Goats / virology*
  • Malignant Catarrh / epidemiology
  • Malignant Catarrh / virology*
  • Molecular Sequence Data
  • Prevalence
  • Sequence Alignment

Associated data

  • GENBANK/AF275941
  • GENBANK/AF275942
  • GENBANK/AF276433