Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. Nov-Dec 2000;22(6):502-5.
doi: 10.1097/00043426-200011000-00005.

Effect of Malnutrition at the Time of Diagnosis on the Survival of Children Treated for Cancer in El Salvador and Northern Brazil

Affiliations

Effect of Malnutrition at the Time of Diagnosis on the Survival of Children Treated for Cancer in El Salvador and Northern Brazil

F Pedrosa et al. J Pediatr Hematol Oncol. .

Abstract

Purpose: To investigate the relationship between survival and malnutrition at the time of diagnosis among children treated for cancer in two developing countries.

Patients and methods: We studied 443 children treated for cancer between 1995 and 1998 at two centers in San Salvador, El Salvador, and Recife, Brazil. Median age at diagnosis was 4.9 years; 283 children had leukemia and 160 had solid tumors. Z-scores were calculated for weight for age (WAZ), height for age (HAZ), and weight for height (WHZ) at diagnosis. Z scores <-2 indicated malnutrition. Patients were also stratified by low-risk disease (solid tumors: stage I, stage II, or localized; acute lymphocytic leukemia: white blood cell count <25,000/microL, no central nervous system involvement, no mediastinal mass and age >1 and <10 yrs) and high-risk disease (all other patients, including those with acute or chronic myelocytic leukemia).

Results: Z-scores indicated malnutrition in 23.5% (WAZ), 22.8% (HAZ), and 15.7% (WHZ) of patients. Z-score was not significantly related to overall survival rates, to survival rates analyzed by type of malignancy or risk status, or to survival rates at the end of the first month of treatment.

Conclusions: We found no relationship between nutritional status and survival in these patients. This implies that future protocols for use in developing countries can be designed to provide optimal treatment intensity despite the high incidence of malnutrition.

Comment in

  • Nutritional status and cancer in childhood.
    Barr RD, Gibson BE. Barr RD, et al. J Pediatr Hematol Oncol. 2000 Nov-Dec;22(6):491-4. doi: 10.1097/00043426-200011000-00003. J Pediatr Hematol Oncol. 2000. PMID: 11132214 Review. No abstract available.

Similar articles

See all similar articles

Cited by 4 articles

Publication types

LinkOut - more resources

Feedback