Correction of the Malabsorption of the Preterm Infant With a Medium-Chain Triglyceride Formula

J Pediatr. 1975 Mar;86(3):446-50. doi: 10.1016/s0022-3476(75)80983-8.

Abstract

After receiving milk-based formula for one week, 16 preterm infants, weighing 1,300 to 1,800 gm, were fed two isocaloric formulas containing either medium-chain or long-chain triglycerides for 15 days; the alternate formula was given for a second period of identical duration. While receiving MCT, the infants had greater (P smaller than 0.01) percent fat absorption (83.4 leads to 97.1%) and weight gain (7.5 leads to 11.5 gm/kg/100 calories). Because metabolic acidosis occurred with the LCT formula, the chloride content was adjusted to that of the MCT were confirmed and, in addition, there was a higher (P smaller than .01) percent retention of nitrogen (67.3 leads to 82.1).

Publication types

  • Clinical Trial
  • Controlled Clinical Trial

MeSH terms

  • Body Weight
  • Celiac Disease / diet therapy
  • Celiac Disease / etiology
  • Dietary Carbohydrates
  • Dietary Fats
  • Dietary Proteins
  • Feces / analysis
  • Humans
  • Infant, Newborn
  • Infant, Premature, Diseases / diet therapy*
  • Intestinal Absorption / drug effects
  • Lipid Metabolism*
  • Malabsorption Syndromes / complications
  • Malabsorption Syndromes / diet therapy*
  • Malabsorption Syndromes / metabolism
  • Nitrogen / analysis
  • Nitrogen / metabolism
  • Nitrogen / urine
  • Triglycerides / pharmacology
  • Triglycerides / therapeutic use*

Substances

  • Dietary Carbohydrates
  • Dietary Fats
  • Dietary Proteins
  • Triglycerides
  • Nitrogen