Fistupyrone, a novel inhibitor of the infection of Chinese cabbage by Alternaria brassicicola, from Streptomyces sp. TP-A0569

J Antibiot (Tokyo). 2000 Oct;53(10):1117-22. doi: 10.7164/antibiotics.53.1117.

Abstract

A new microbial metabolite, designated fistupyrone, was isolated from the culture broth of a plant-associated Streptomyces sp. TP-A0569. Fistupyrone inhibited the in vivo infection of the seedlings of Chinese cabbage by Alternaria brassicicola TP-F0423, the cause of Alternaria leaf spot, without any in vitro fungicidal activity.

MeSH terms

  • Alternaria / drug effects*
  • Alternaria / pathogenicity
  • Antifungal Agents / chemistry
  • Antifungal Agents / isolation & purification
  • Antifungal Agents / metabolism
  • Antifungal Agents / pharmacology*
  • Brassica / microbiology*
  • Pest Control, Biological
  • Plant Diseases / microbiology*
  • Pyrones / chemistry
  • Pyrones / isolation & purification
  • Pyrones / metabolism
  • Pyrones / pharmacology*
  • Streptomyces / classification*
  • Streptomyces / growth & development
  • Streptomyces / metabolism*

Substances

  • Antifungal Agents
  • Pyrones
  • fistupyrone