Protein-specific chaperones: the role of hsp47 begins to gel

Curr Biol. 2000 Dec 14-28;10(24):R912-5. doi: 10.1016/s0960-9822(00)00850-2.

Abstract

Collagen biosynthesis involves a complex series of post-translational modifications, controlled by a number of general and specific molecular chaperones. A recent study has shed new light on the role played in this process by the procollagen-specific chaperone Hsp47.

Publication types

  • Review

MeSH terms

  • Animals
  • Collagen / biosynthesis*
  • Collagen / metabolism
  • Endoplasmic Reticulum / enzymology
  • Endoplasmic Reticulum / metabolism*
  • Heat-Shock Proteins / genetics
  • Heat-Shock Proteins / metabolism*
  • Models, Biological
  • Molecular Chaperones / metabolism*
  • Protein Processing, Post-Translational / physiology*
  • Protein Transport

Substances

  • Heat-Shock Proteins
  • Molecular Chaperones
  • Collagen