Mitosis: a history of division

Nat Cell Biol. 2001 Jan;3(1):E17-21. doi: 10.1038/35050656.


Mitosis has been studied since the early 1880s, to the extent that we now have a detailed, but still incomplete, description of spindle dynamics and mechanics, a sense of potential mechanochemical and regulatory mechanisms at a molecular level, and a long list of mitotic proteins. Here we present a personal view of how far we have come, and where we need to go to fully understand the mechanisms involved in mitosis.

Publication types

  • Historical Article
  • Review

MeSH terms

  • Animals
  • Genetics / history*
  • History, 19th Century
  • History, 20th Century
  • Humans
  • Mitosis*