Enteric-coated, pH-dependent peppermint oil capsules for the treatment of irritable bowel syndrome in children

J Pediatr. 2001 Jan;138(1):125-8. doi: 10.1067/mpd.2001.109606.

Abstract

In a randomized, double-blind controlled trial, 42 children with irritable bowel syndrome (IBS) were given pH-dependent, enteric-coated peppermint oil capsules or placebo. After 2 weeks, 75% of those receiving peppermint oil had reduced severity of pain associated with IBS. Peppermint oil may be used as a therapeutic agent during the symptomatic phase of IBS.

Publication types

  • Clinical Trial
  • Multicenter Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Abdominal Pain / diagnosis
  • Abdominal Pain / etiology
  • Adolescent
  • Age Factors
  • Child
  • Colonic Diseases, Functional / complications
  • Colonic Diseases, Functional / drug therapy*
  • Colonic Diseases, Functional / physiopathology
  • Double-Blind Method
  • Female
  • Humans
  • Hydrogen-Ion Concentration
  • Male
  • Pain Measurement
  • Parasympatholytics / therapeutic use*
  • Plant Oils / therapeutic use*
  • Severity of Illness Index
  • Tablets, Enteric-Coated / therapeutic use*
  • Treatment Outcome

Substances

  • Parasympatholytics
  • Plant Oils
  • Tablets, Enteric-Coated
  • peppermint oil