Computed tomography (CT) and magnetic resonance imaging (MRI) are modalities well suited for imaging of the pericardium and pericardial disease. Both offer excellent resolution with a wide field of view. Both have advantages and disadvantages when compared with each other and with echocardiography. Establishing the diagnosis of constrictive pericarditis is a common indication for CT or MRI of the pericardium. Pericarditis, neoplasms, effusions, and congenital anomalies are additional conditions involving the pericardium that can be diagnosed with CT and MRI.