A-V conduction disturbances in Reiter's syndrome

Am J Med. 1975 Feb;58(2):280-4. doi: 10.1016/0002-9343(75)90578-1.


High grade atrioventricular (A-V) block is a rarely described complication of Reiter's syndrome. This 65 year old man had recurrent episodes of arthritis, conjunctivitis and urethritis beginning at age 16. A prolonged P-R interval was first noted at age 32. The conduction distrubance progressed to intermittent episodes of high grade and complete heart block by age 65. His bundle electrograms located the site of block above the level of the bundle of His. Atrial pacing to rates of 150/min produced 5:1 A-V block, whereas exercise and atropine administration resulted in 1:1 A-V conduction. In view of these results, artificial pacemaker therapy is not indicated. The association of conduction disorders and Reiter's syndrome is reviewed.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Aged
  • Arthritis, Reactive / complications*
  • Arthritis, Reactive / diagnosis
  • Arthritis, Reactive / physiopathology
  • Atrioventricular Node* / physiopathology
  • Atropine / therapeutic use
  • Bundle of His / physiopathology
  • Electrocardiography
  • Electrophysiology
  • Exercise Therapy
  • Heart Block / diagnosis
  • Heart Block / drug therapy
  • Heart Block / etiology*
  • Heart Block / therapy
  • Heart Conduction System*
  • Humans
  • Male


  • Atropine