Structure comparison and structure patterns

J Comput Biol. 2000;7(5):685-716. doi: 10.1089/106652701446152.


This article investigates aspects of pairwise and multiple structure comparison, and the problem of automatically discover common patterns in a set of structures. Descriptions and representation of structures and patterns are described, as well as scoring and algorithms for comparison and discovery. A framework and nomenclature is developed for classifying different methods, and many of these are reviewed and placed into this framework.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms*
  • Cluster Analysis
  • Databases, Factual
  • Molecular Structure
  • Proteins / chemistry*
  • Sequence Alignment / methods
  • Sequence Alignment / statistics & numerical data


  • Proteins