Innate immunity in plants

Curr Opin Immunol. 2001 Feb;13(1):55-62. doi: 10.1016/s0952-7915(00)00182-5.


Studies of receptors and signal-transduction components that play a role in plant disease resistance have revealed remarkable similarities with innate immunity pathways in insects and mammals. In plants, specific receptors encoded by disease-resistance genes interact with products of microbial effector genes to activate defence responses. Resistance proteins have been found to have motifs in common with components of immune response pathways in mammals and invertebrates, and to rely on similar downstream signalling components. In the future, the sharing of ideas among plant and animal biologists is likely to broaden our understanding of defence responses in diverse organisms.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Animals
  • Humans
  • Immunity, Innate / immunology*
  • Plant Diseases* / genetics
  • Plant Diseases* / microbiology
  • Plant Diseases* / parasitology
  • Plant Diseases* / virology
  • Plants / immunology*