Primary viscocanalostomy versus trabeculectomy in white patients with open-angle glaucoma: A randomized clinical trial

Ophthalmology. 2001 Feb;108(2):254-8. doi: 10.1016/s0161-6420(00)00514-5.


Purpose: To compare viscocanalostomy, a nonpenetrating procedure for glaucoma treatment, with trabeculectomy.

Design: Randomized controlled trial.

Participants: Twenty white subjects (20 eyes) with open-angle glaucoma with no history of surgery were enrolled.

Methods: Ten subjects were randomly assigned to viscocanalostomy according to Stegmann's technique and 10 subjects to a modified Cairns trabeculectomy. A complete ophthalmologic examination was performed the day before surgery and postoperatively. Further visits were scheduled monthly for 6 to 8 months after surgery.

Main outcome measures: Success was defined as intraocular pressure (IOP) between 7 and 20 mmHg, with no medication.

Results: After a mean follow-up of 6 months (range, 6-8 months), success was obtained in 5 of 10 cases in the trabeculectomy group and in no case in the viscocanalostomy group. With Kaplan-Meier's method, subjects with viscocanalostomy showed shorter postoperative IOP-reduction periods than subjects undergoing trabeculectomy.

Conclusions: According to the results of this short-term study, trabeculectomy was more effective than viscocanalostomy in lowering IOP in glaucomatous eyes of white patients.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Aged
  • Anterior Eye Segment / surgery*
  • Female
  • Follow-Up Studies
  • Glaucoma, Open-Angle / ethnology
  • Glaucoma, Open-Angle / surgery*
  • Gonioscopy
  • Humans
  • Hyaluronic Acid / administration & dosage
  • Intraocular Pressure
  • Male
  • Middle Aged
  • Prospective Studies
  • Surgical Flaps
  • Trabeculectomy / methods*
  • Treatment Outcome
  • White People*


  • Hyaluronic Acid