Therapeutic potential of inhibition of the NF-kappaB pathway in the treatment of inflammation and cancer

J Clin Invest. 2001 Jan;107(2):135-42. doi: 10.1172/JCI11914.
No abstract available

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Alzheimer Disease / etiology
  • Anti-Inflammatory Agents / therapeutic use*
  • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
  • Antineoplastic Agents / therapeutic use*
  • Apoptosis / genetics
  • Arthritis, Rheumatoid / etiology
  • Asthma / etiology
  • Cell Division / genetics
  • Chemokines / biosynthesis
  • Chemokines / genetics
  • Cyclooxygenase 2
  • Cytokines / biosynthesis
  • Cytokines / genetics
  • Glucocorticoids / therapeutic use
  • I-kappa B Kinase
  • I-kappa B Proteins / metabolism
  • Immunosuppressive Agents / therapeutic use
  • Inflammatory Bowel Diseases / etiology
  • Isoenzymes / biosynthesis
  • Isoenzymes / genetics
  • NF-kappa B / antagonists & inhibitors
  • NF-kappa B / immunology
  • NF-kappa B / physiology*
  • Nitric Oxide Synthase / biosynthesis
  • Nitric Oxide Synthase / genetics
  • Nitric Oxide Synthase Type II
  • Phosphorylation
  • Prostaglandin-Endoperoxide Synthases / biosynthesis
  • Prostaglandin-Endoperoxide Synthases / genetics
  • Protein-Serine-Threonine Kinases / metabolism
  • Signal Transduction

Substances

  • Anti-Inflammatory Agents
  • Anti-Inflammatory Agents, Non-Steroidal
  • Antineoplastic Agents
  • Chemokines
  • Cytokines
  • Glucocorticoids
  • I-kappa B Proteins
  • Immunosuppressive Agents
  • Isoenzymes
  • NF-kappa B
  • Nitric Oxide Synthase
  • Nitric Oxide Synthase Type II
  • Cyclooxygenase 2
  • Prostaglandin-Endoperoxide Synthases
  • Protein-Serine-Threonine Kinases
  • I-kappa B Kinase