Dynamics of electroencephalographic slow wave activity and body temperature during monophasic and biphasic human sleep

Neurosci Lett. 2001 Feb 2;298(2):83-6. doi: 10.1016/s0304-3940(00)01686-4.


Dynamics of electroencephalographic (EEG) slow wave activity (0.5-4.5 Hz) and body temperature, as estimates, respectively, of the process S and process C, regulating sleep and waking alternate occurrence, were measured during monophasic and biphasic sleep patterns that occurred spontaneously in a 35-year-old woman who lived for 105 days in a winter-type photoperiod (10-14 h light-dark). In monophasic nights, rate of EEG synchronization showed a decreasing trend across the first three non-rapid eye movement (NREM) periods. In biphasic nights, rate of EEG synchronization increased during the third NREM period which precedes the nocturnal awakening. Temperature cycle was not different between biphasic and monophasic nights. Those results confirm that EEG dynamics reflects homeostatic sleep regulatory mechanism, and suggest that the period of prolonged wakefulness in the middle of biphasic night is pre-programmed.

MeSH terms

  • Adult
  • Body Temperature / physiology*
  • Brain / physiology
  • Electroencephalography*
  • Female
  • Homeostasis / physiology
  • Humans
  • Sleep / physiology*
  • Wakefulness / physiology