Review
doi: 10.1016/s0361-9230(00)00388-9.
Differentiation of electrical excitability in motoneurons
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- PMID: 11165790
- DOI: 10.1016/s0361-9230(00)00388-9
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Review
Differentiation of electrical excitability in motoneurons
Brain Res Bull.
.
Abstract
Investigation of the differentiation of electrical properties of motoneurons has been stimulated by the importance of these neurons for embryonic behavior and facilitated by their experimental accessibility. In this review, we examine the development of different patterns of excitability and their functions, and discuss the emergence of repetitive firing and localization of ion channels in axons and dendrites. Finally, we summarize studies of the role of extrinsic factors in differentiation. These changes associated with differentiation of young motoneurons may presage those occurring later in the context of plasticity in the mature nervous system.
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