Nonsteroidal anti-inflammatory drug prescribing: past, present, and future

Am J Med. 2001 Jan 8;110(1A):4S-7S. doi: 10.1016/s0002-9343(00)00627-6.


Nonsteroidal anti-inflammatory drugs, including aspirin, are now among the most widely prescribed medications in the world. They have a long and fascinating history, with the use of aspirin derived from willow bark stretching back into the Assyrian culture. In the twenty-first century we are faced with both the challenge of balancing the benefits and side effects of these drugs and the exciting prospect of new, safer agents with comparable efficacy.

Publication types

  • Historical Article
  • Review

MeSH terms

  • Anti-Inflammatory Agents, Non-Steroidal / history*
  • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
  • Aspirin / history*
  • Aspirin / therapeutic use
  • Drug Prescriptions / history
  • Drug Prescriptions / statistics & numerical data
  • Europe
  • History, 18th Century
  • History, 19th Century
  • History, 20th Century
  • History, Ancient
  • History, Medieval
  • Humans


  • Anti-Inflammatory Agents, Non-Steroidal
  • Aspirin