Tumor progression: defining the soil round the tumor seed

Curr Biol. 2001 Jan 9;11(1):R25-7. doi: 10.1016/s0960-9822(00)00038-5.


The tumor microenvironment, or stroma, is known to contribute to tumor progression. Two recent studies have shown that the stromal protein matrix metalloproteinase MMP-9 has a role in the early stages of tumor growth and angiogenesis.

Publication types

  • Review

MeSH terms

  • Disease Progression
  • Matrix Metalloproteinase 9 / physiology
  • Neoplasms / blood supply
  • Neoplasms / pathology*
  • Neovascularization, Pathologic


  • Matrix Metalloproteinase 9