RUN domains: a new family of domains involved in Ras-like GTPase signaling

I Callebaut; J de Gunzburg; B Goud; J P Mornon

doi:10.1016/s0968-0004(00)01730-8

RUN domains: a new family of domains involved in Ras-like GTPase signaling

Trends Biochem Sci. 2001 Feb;26(2):79-83. doi: 10.1016/s0968-0004(00)01730-8.

Authors

I Callebaut¹, J de Gunzburg, B Goud, J P Mornon

Affiliation

¹ Systèmes moléculaires et Biologie structurale, CNRS UMR 7590, Universités Paris 6 & Paris 7, case 115, 4 place Jussieu, 75252 Paris 05, Cedex, France.

PMID: 11166556
DOI: 10.1016/s0968-0004(00)01730-8

Abstract

RUN domains are present in several proteins that are linked particularly to the functions of GTPases in the Rap and Rab families. They could hence play an important role in multiple Ras-like GTPase signaling pathways.

MeSH terms

Amino Acid Sequence
Animals
GTP Phosphohydrolases / metabolism*
Genome
Humans
Molecular Sequence Data
Protein Structure, Tertiary
Sequence Homology, Amino Acid
Signal Transduction*
ras Proteins / chemistry*

Substances

GTP Phosphohydrolases
ras Proteins