Superficial esophageal carcinoma: an in vitro study of high-resolution MR imaging at 1.5T

J Magn Reson Imaging. 2001 Feb;13(2):225-31. doi: 10.1002/1522-2586(200102)13:2<225::aid-jmri1033>3.0.co;2-z.

Abstract

The purpose of this study was to determine the diagnostic accuracy of high-resolution MR imaging at 1.5T for evaluating the mural invasion of superficial esophageal carcinoma. Forty-one esophageal specimens taken from patients suspected of having superficial carcinoma were studied using a 1.5T MR system with a surface coil. Spin-echo MR images were obtained with a field of view of 50mm, matrix of 256 x 256, and section thickness of 2mm (voxel size = 0.08 mm3). MR findings were compared with histopathologic findings. T2-weighted images clearly depicted the normal esophageal wall as consisting of 8 layers. In 39 (95%) of 41 carcinomas, the depth of mural invasion determined by MR imaging correlated well with that determined with histopathologic examination. The MR-based stage was higher in 2 (5%) cases than the histopathologic stage. High-resolution MR imaging at 1.5T shows a high diagnostic accuracy for evaluating the mural invasion of superficial esophageal carcinoma, thus potentially enabling preoperative histopathologic staging.

MeSH terms

  • Adult
  • Aged
  • Carcinoma, Squamous Cell / diagnosis*
  • Carcinoma, Squamous Cell / pathology
  • Esophageal Neoplasms / diagnosis*
  • Esophageal Neoplasms / pathology
  • Esophagus / pathology
  • Female
  • Humans
  • Image Enhancement*
  • Magnetic Resonance Imaging*
  • Male
  • Middle Aged
  • Neoplasm Invasiveness
  • Neoplasm Staging
  • Sensitivity and Specificity