Langerhans cell histiocytosis infiltration in cerebrospinal fluid: a case report

Diagn Cytopathol. 2001 Feb;24(2):123-5. doi: 10.1002/1097-0339(200102)24:2<123::aid-dc1023>3.0.co;2-u.

Abstract

Langerhans cell histiocytosis (LCH) is a disease of unknown etiology characterized by a proliferation of histiocytic cells resembling the integumentary cells bearing the name of Langerhans cells. LCH can be unifocal or multifocal, with one- or many-organ involvement. We present a case of LCH diagnosed in the cerebrospinal fluid of a patient with generalized lymphadenopathy and central nervous system involvement.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Brain Infarction / etiology
  • Brain Infarction / pathology
  • Cysts / etiology
  • Cysts / pathology
  • Cytodiagnosis
  • Histiocytes / metabolism
  • Histiocytes / pathology
  • Histiocytosis, Langerhans-Cell / cerebrospinal fluid*
  • Histiocytosis, Langerhans-Cell / complications
  • Histiocytosis, Langerhans-Cell / metabolism
  • Histiocytosis, Langerhans-Cell / pathology
  • Humans
  • Immunohistochemistry
  • Langerhans Cells / metabolism
  • Langerhans Cells / pathology
  • Lymph Nodes / pathology
  • Lymphatic Diseases / etiology
  • Lymphatic Diseases / pathology
  • Male
  • Meningitis / etiology
  • Meningitis / pathology
  • S100 Proteins / metabolism

Substances

  • S100 Proteins