Abstract
Langerhans cell histiocytosis (LCH) is a disease of unknown etiology characterized by a proliferation of histiocytic cells resembling the integumentary cells bearing the name of Langerhans cells. LCH can be unifocal or multifocal, with one- or many-organ involvement. We present a case of LCH diagnosed in the cerebrospinal fluid of a patient with generalized lymphadenopathy and central nervous system involvement.
Copyright 2001 Wiley-Liss, Inc.
MeSH terms
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Adult
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Brain Infarction / etiology
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Brain Infarction / pathology
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Cysts / etiology
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Cysts / pathology
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Cytodiagnosis
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Histiocytes / metabolism
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Histiocytes / pathology
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Histiocytosis, Langerhans-Cell / cerebrospinal fluid*
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Histiocytosis, Langerhans-Cell / complications
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Histiocytosis, Langerhans-Cell / metabolism
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Histiocytosis, Langerhans-Cell / pathology
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Humans
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Immunohistochemistry
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Langerhans Cells / metabolism
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Langerhans Cells / pathology
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Lymph Nodes / pathology
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Lymphatic Diseases / etiology
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Lymphatic Diseases / pathology
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Male
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Meningitis / etiology
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Meningitis / pathology
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S100 Proteins / metabolism