Aromatization of androstenedione by isolated human hairs

J Clin Endocrinol Metab. 1975 Mar;40(3):413-7. doi: 10.1210/jcem-40-3-413.

Abstract

The formation of (3-H) estrone has been demonstrated in human anagen scalp hair roots incubated with (1, 2, 6, 7-3H) androstenedione, and approximate rates of formation of 0.2 pmol of estrone/mg DNA/h were observed. Thus, hair is a potential site for the extraglandular formation of estrogen in man.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Androstenedione / metabolism*
  • Chromatography, Thin Layer
  • DNA / analysis
  • Estrone / metabolism*
  • Hair / metabolism*
  • Humans
  • In Vitro Techniques
  • Male
  • Time Factors

Substances

  • Estrone
  • Androstenedione
  • DNA