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. 2001 Jan;64(1):125-6.
doi: 10.1021/np000381u.

Circumdatin G, a new alkaloid from the fungus Aspergillus ochraceus

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Circumdatin G, a new alkaloid from the fungus Aspergillus ochraceus

J Dai et al. J Nat Prod. 2001 Jan.

Abstract

The crude extract of the broth of Aspergillus ochraceus was found to inhibit the final stage of polyprotein processing during hepatitis C virus replication. Bioassay-guided fractionation led to the isolation of the known compound mellein as the active component of the extract. Also isolated were circumdatin F and a new alkaloid, circumdatin G. The structure of circumdatin G was determined by spectroscopic analysis.

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