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, 353 (Pt 3), 441-4

An Uncoupling Protein Homologue Putatively Involved in Facultative Muscle Thermogenesis in Birds

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An Uncoupling Protein Homologue Putatively Involved in Facultative Muscle Thermogenesis in Birds

S Raimbault et al. Biochem J.

Abstract

The cDNA of an uncoupling protein (UCP) homologue was obtained by screening a chicken skeletal-muscle library. The predicted 307-amino-acid sequence of avian UCP (avUCP) is 55, 70, 70 and 46% identical with mammalian UCP1, UCP2 and UCP3 and plant UCP respectively. avUCP mRNA expression is restricted to skeletal muscle and its abundance was increased 1.3-fold in a chicken line showing diet-induced thermogenesis, and 3.6- and 2.6-fold in cold-acclimated and glucagon-treated ducklings developing muscle non-shivering thermogenesis respectively. The present data support the implication of avUCP in avian energy expenditure.

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References

    1. FEBS Lett. 1998 Nov 20;439(3):258-62 - PubMed
    1. Proc Natl Acad Sci U S A. 1998 Mar 31;95(7):4061-5 - PubMed
    1. EMBO J. 1999 Nov 1;18(21):5827-33 - PubMed
    1. Biochem J. 2000 Jan 15;345 Pt 2:161-79 - PubMed
    1. Diabetes. 2000 Feb;49(2):143-56 - PubMed

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