Usefulness of diabetic retinopathy as a marker of risk for thallium myocardial perfusion defects in non-insulin-dependent diabetes mellitus

Am J Cardiol. 2001 Feb 15;87(4):456-9, A6. doi: 10.1016/s0002-9149(00)01404-1.


Among 236 non-insulin-dependent diabetics with clinically suspected coronary artery disease, the rate of thallium-201 myocardial perfusion defects was significantly higher in subjects with (40.6%) than without (22.1%) diabetic retinopathy. Retinopathy was associated with a higher risk of perfusion defects in subjects with cardiac and noncardiac chest pain, and may thus be a useful marker for selecting patients in whom thallium scintigraphy screening is warranted.

MeSH terms

  • Chi-Square Distribution
  • Coronary Angiography
  • Coronary Disease / diagnostic imaging*
  • Coronary Disease / etiology*
  • Diabetes Mellitus, Type 2 / complications*
  • Diabetic Retinopathy / complications*
  • Female
  • Humans
  • Logistic Models
  • Male
  • Middle Aged
  • Predictive Value of Tests
  • Retrospective Studies
  • Risk Factors
  • Thallium Radioisotopes
  • Tomography, Emission-Computed, Single-Photon


  • Thallium Radioisotopes