DPKQDFMRFamide expression is similar in two distantly related Drosophila species

J Friedman; J Starkman; R Nichols

doi:10.1016/s0196-9781(00)00387-9

DPKQDFMRFamide expression is similar in two distantly related Drosophila species

Peptides. 2001 Feb;22(2):235-9. doi: 10.1016/s0196-9781(00)00387-9.

Authors

J Friedman¹, J Starkman, R Nichols

Affiliation

¹ Undergraduate Cell and Molecular Biology Program, University of Michigan, Ann Arbor, MI 48109-1048, USA.

PMID: 11179817
DOI: 10.1016/s0196-9781(00)00387-9

Abstract

Drosophila melanogaster DPKQDFMRFamide was isolated and its expression reported. Distribution of DPKQDFMRFamide immunoreactivity is now described in Drosophila virilis. DPKQDFMRFamide antibody stained a cell in the subesophageal ganglion in embryo. DPKQDFMRFamide antibody stained cells in the superior protocerebrum, subesophageal ganglion, thoracic ganglia, and an abdominal ganglion in larva, pupa, and adult. DPKQDFMRFamide antibody stained an additional pair of cells in the optic lobe and a cell in the lateral protocerebrum in adult. Structure identity and similar distribution of DPKQDFMRFamide in D. virilis and D. melanogaster, two distantly related Drosophila species, suggests an important and conserved activity for the peptide.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Animals
Drosophila / physiology*
FMRFamide / physiology*
Immunohistochemistry

Substances

FMRFamide