Effect of breath holding on blood flow measurement using fast velocity encoded cine MRI

Magn Reson Med. 2001 Feb;45(2):346-8. doi: 10.1002/1522-2594(200102)45:2<346::aid-mrm1044>3.0.co;2-i.

Abstract

Breath-hold MR measurement of cardiac output was compared with results from respiratory triggered MR acquisitions, since flow measurement during breath-holding may be different from physiological blood flow. Cardiac output during large lung volume breath-holding (4.47 +/- 0.63 l/min in the aorta and 4.53 +/- 0.59 l/min in the pulmonary artery) was significantly lower than that measured during normal breathing (6.09 +/- 0.49 l/min and 6.48 +/- 0.67 l/min, P < 0.01). In contrast, no significant difference was found between measurements conducted with small lung volume breath-holding (5.87 +/- 0.53 l/min and 6.41 +/- 0.75 l/min) and normal breathing. In conclusion, breath-hold MR flow measurement using small lung volume by shallow inspiration can provide a blood flow quantification that is close to physiological blood flow. Magn Reson Med 45:346-348, 2001.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Blood Circulation / physiology*
  • Cardiac Output / physiology
  • Female
  • Humans
  • Magnetic Resonance Imaging, Cine / methods*
  • Male
  • Respiratory Physiological Phenomena*