Surgical intervention as a strategy for treatment of obesity

Endocrine. 2000 Oct;13(2):213-30. doi: 10.1385/ENDO:13:2:213.


A very large number of weight-reducing surgical techniques have been developed over the last 25 years. Today only a handful of these techniques can be recommended. Gastric bypass, vertical banded gastroplasty, and variable banding can all be recommended although gastric bypass should be reserved for heavier patients. For the heaviest, biliopancreatic diversion or biliopancreatic diversion with duodenal switch might be considered. The controlled intervention study Swedish Obese Subjects has shown that most but not all cardiovascular risk factors are improved over 10 years by surgically induced weight loss. Quality of life as well as cardiac structure and function are dramatically improved. The average weight loss for gastric bypass and vertical banded gastroplasty was 16% after 10 years. No non-surgical treatment available today can achieve such results, not even over 2 years. Surgical treatment for obesity needs to become much more common, particularly in obese patients with metabolic disturbances.

Publication types

  • Review

MeSH terms

  • Biliopancreatic Diversion
  • Body Mass Index
  • Body Weight
  • Cardiovascular Diseases / etiology
  • Cardiovascular Diseases / prevention & control
  • Gastric Bypass
  • Gastroplasty
  • Humans
  • Obesity / complications
  • Obesity / surgery*
  • Obesity, Morbid / surgery
  • Postoperative Complications
  • Weight Loss