The acute fatty liver of pregnancy is a specific disease of pregnancy. Its incidence is rare but prognosis is poor in complicated entities, and can compromise the foetal and maternal life. An early diagnosis of the illness and a multidisciplinary management based on uterine evacuation and an intensive medical care can improve the prognosis of the acute fatty liver of pregnancy (A.F.L.P). In hope to contribute at a better approach of this affection, the authors report their experience about 3 cases of A.F.L.P., collected in 1997.