Compilation and characterization of histidine-containing phosphotransmitters implicated in His-to-Asp phosphorelay in plants: AHP signal transducers of Arabidopsis thaliana

Biosci Biotechnol Biochem. 2000 Nov;64(11):2486-9. doi: 10.1271/bbb.64.2486.


Histidine (His)-to-Aspartate (Asp) phosphorelay signal transduction systems are generally made up of a "sensor histidine (His)-kinase", a "response regulator", and a "histidine-containing phosphotransmitter (HPt)". In the higher plant, Arabidopsis thaliana, results from recent intensive studies suggested that the His-to-Asp phosphorelay mechanism is at least partly responsible for propagation of environmental stimuli, such as phytohormones (e.g. ethylene and cytokinin). Here we compiled the members of the HPt family of phosphotransmitters in Arabidopsis thaliana (AHP-series, Arabidopsis HPt phosphotransmitters), based on both database and experimental analyses, in order to provide a comprehensive basis at the molecular level for understanding the function of the AHP phosphotransmitters that are implicated in the His-to-Asp phosphorelay of higher plants.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Arabidopsis / metabolism*
  • Arabidopsis Proteins*
  • Aspartic Acid / metabolism
  • Cell Cycle Proteins*
  • Histidine / metabolism
  • Histidine Kinase
  • Molecular Sequence Data
  • Phosphotransferases*
  • Plant Proteins / metabolism*
  • Protein Kinases / metabolism*
  • Schizosaccharomyces pombe Proteins*
  • Sequence Homology, Amino Acid
  • Signal Transduction


  • AHP1 protein, Arabidopsis
  • Arabidopsis Proteins
  • Cell Cycle Proteins
  • Plant Proteins
  • Schizosaccharomyces pombe Proteins
  • Aspartic Acid
  • Histidine
  • Phosphotransferases
  • Protein Kinases
  • Mpr1 protein, S pombe
  • Histidine Kinase