Clara cell proteins

Ann N Y Acad Sci. 2000;923:43-58. doi: 10.1111/j.1749-6632.2000.tb05518.x.

Abstract

Clara cells are nonciliated, nonmucous, secretory cells of the pulmonary airways. These cells are known to secrete a variety of proteins, including Clara cell 10-kDa protein/uteroglobin. This protein consists of a homodimer of 70-77 amino acid polypeptides arranged in antiparallel fashion. In vitro testing suggests that the protein suppresses inflammation. The physiologic role of the protein remains to be determined.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Animals
  • Humans
  • Proteins / metabolism*
  • Respiratory Mucosa / metabolism*
  • Uteroglobin*

Substances

  • Proteins
  • SCGB1A1 protein, human
  • Uteroglobin