Chemical synthesis of UDP-beta-L-arabinofuranose and its turnover to UDP-beta-L-arabinopyranose by UDP-galactopyranose mutase

Bioorg Med Chem Lett. 2001 Jan 22;11(2):145-9. doi: 10.1016/s0960-894x(00)00616-8.


Uridine-5'-diphospho-beta-L-arabinofuranose, a possible donor of L-arabinofuranose residues in plants, was synthesized. This compound, in the presence of UDP-galactopyranose mutase, underwent interconversion with UDP-beta-L-arabinopyranose that is a likely precursor of L-arabinofuranose in vivo. This result provided a working model for the biogenesis of arabinofuranose in plants.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Chromatography, High Pressure Liquid
  • Intramolecular Transferases / metabolism*
  • Plants / chemistry
  • Uridine Diphosphate Galactose / metabolism
  • Uridine Diphosphate Sugars / chemical synthesis
  • Uridine Diphosphate Sugars / metabolism*


  • Uridine Diphosphate Sugars
  • uridine diphosphate arabinose
  • Uridine Diphosphate Galactose
  • Intramolecular Transferases