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. 2000 Dec;64(12):2559-68.
doi: 10.1271/bbb.64.2559.

Nematicidal alkaloids and related compounds produced by the fungus Penicillium cf. simplicissimum

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Free article

Nematicidal alkaloids and related compounds produced by the fungus Penicillium cf. simplicissimum

M Kusano et al. Biosci Biotechnol Biochem. 2000 Dec.
Free article

Abstract

A new nematicidal alkaloid, peniprequinolone (1), together with the known alkaloids penigequinolones A and B (2a, 2b), 3-methoxy-4-hydroxy-4-(4'-methoxyphenyl)quinolinone (3), and 3-methoxy-4,6-dihydroxy-4-(4'-methoxyphenyl)quinolinone (4), were isolated from Penicillium cf. simplicissimum (Oudemans) Thom. Cyclopenin (5) and a compound (6a/6b) structurally related to cyclopenin also were isolated from the fungus, and their structures were established by spectroscopic analysis. The biological activities of 1, 2, 3, 4, and 5 were examined by a bioassay with root-lesion nematodes.

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