Characterization of a vitamin B12 compound in the edible purple laver, Porphyra yezoensis

Biosci Biotechnol Biochem. 2000 Dec;64(12):2712-5. doi: 10.1271/bbb.64.2712.


The edible purple laver, Porphyra yezoensis, contained 51.49+/-1.51 microg of vitamin B12 compounds per 100 g dry weight of the laver (mean +/- SEM, n = 4). A vitamin B12 compound was purified from the lyophilized purple laver and partially characterized. The silica gel 60 TLC and reversed-phase HPLC patterns of the purified pink-colored compound were identical to those of authentic vitamin B12, but not to those of vitamin B12 analogues inactive for humans.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biological Availability
  • Chromatography, High Pressure Liquid
  • Chromatography, Thin Layer
  • Luminescent Measurements
  • Seaweed / chemistry*
  • Spectrophotometry, Ultraviolet
  • Vitamin B 12 / chemistry*
  • Vitamin B 12 / isolation & purification
  • Vitamin B 12 / pharmacokinetics


  • Vitamin B 12